Club Brugge will be taking on Aston Villa at the occasion of the Champions League Round of 16. For this first leg encounter, coach Hayen selected the following 22 players.
- 22. Simon Mignolet
- 29. Nordin Jackers
- 71. Axl De Corte
- 44. Brandon Mechele
- 04. Joel Ordóñez
- 02. Zaid Romero
- 58. Jorne Spileers
- 55. Maxim De Cuyper
- 64. Kyriani Sabbe
- 41. Hugo Siquet
- 30. Ardon Jashari
- 27. Casper Nielsen
- 15. Raphael Onyedika
- 20. Hans Vanaken
- 10. Hugo Vetlesen
- 21. Michał Skóraś
- 68. Chemsdine Talbi
- 08. Christos Tzolis
- 84. Shandre Campbell
- 09. Ferran Jutglà
- 19. Gustaf Nilsson
- 17. Romeo Vermant